Botulinum Toxin is a neurotoxin derived from the bacterium Clostridium Botulinum, widely used in many areas, particularly in wrinkle treatment. Its wrinkle-reducing effect by relaxing the muscles has been approved by the FDA* (U.S. Food and Drug Administration). Botulinum Toxin has been used in Turkey since the 1990s. On this page, you can find the most detailed information and explanations about the Botulinum Toxin (wrinkle treatment) method.

How is Wrinkle Treatment Applied?

Botulinum Toxin blocks the release of acetylcholine, causing the muscles in the treated area to relax and the wrinkles to diminish. With this special formula that keeps the skin tight, you too can eliminate the wrinkles on your face. The wrinkle treatment is performed without the need for anesthesia, and there is no pain during or after the procedure. Once the treatment area is thoroughly cleansed, Botulinum Toxin is injected in small doses into the muscles with fine needles. The procedure takes about 30 minutes, and patients can immediately return to their daily activities. During the injection, only a slight stinging sensation may be felt when the needle touches the skin — this is the only discomfort experienced. After the session, patients are advised not to massage the treated area or overuse the facial muscles.

Duration of Effect

Patients should know that the effect of Botulinum Toxin lasts about 6 months and must be repeated at regular intervals. Results usually begin to appear within two days of the application. For first-time patients, a second session after 3–4 months may provide more effective outcomes. With regular treatments, repeating the procedure once or twice a year ensures successful wrinkle reduction. The most visible results are within the first 3–4 months, after which wrinkles may gradually reappear. Follow-up sessions will have longer-lasting effects.

Application Areas

Botulinum Toxin is commonly applied to: Eyes – Between the eyebrows – Neck – Forehead – Chin and lips. Although it is mainly used on the face and surrounding areas, a consultation with your doctor is essential before treatment. The success of this procedure depends not only on the material used but also on the doctor’s experience and application technique.

Pricing

The cost of Botulinum Toxin varies depending on the purpose of treatment. In addition to wrinkle treatment, it is also used for excessive sweating and migraine therapy. For accurate pricing, a consultation is required. You can call +90 (232) 421 30 64 for detailed information and to ask our specialists any questions regarding Botulinum Toxin.

Less-Known Uses

Although it is widely known today for its cosmetic and wrinkle-reducing effects, Botulinum Toxin also plays an important role in medical treatments. It is used in patients with paralysis, muscle spasm disorders, involuntary facial movements, and strabismus. Additionally, it is an effective solution for excessive sweating and migraine headaches.

Why Do Wrinkles Occur?

Facial muscles are constantly in motion. Over time, this repeated movement leads to permanent changes in the skin and the formation of wrinkles, also known as "dynamic lines." These are often seen as horizontal lines on the forehead, fine lines between the eyebrows, and "crow’s feet" around the eyes.

Effective in Migraine Treatment

The effectiveness of Botulinum Toxin in relieving migraine headaches was discovered by coincidence. Patients reported that their migraine pain disappeared after receiving Botox for wrinkles. Further studies confirmed that Botulinum Toxin relaxes the tense muscles in the head area that trigger severe headaches. Within a week of treatment, migraine symptoms may disappear, and the effect lasts for approximately six months.

Excessive Sweating (Hyperhidrosis)

Botulinum Toxin prevents excessive sweating by blocking the signals between nerves and sweat glands. When applied to sweat glands, it can stop excessive sweating in the underarms, palms, and soles of the feet, and also eliminates unpleasant odor. Unlike wrinkle treatment, the effect in hyperhidrosis treatment can last up to one year.

History of Botulinum Toxin – Did You Know?
The foundations of Botulinum Toxin were laid in 1817 by German physician Justinus Kerner. In 1895, another German scientist identified Clostridium botulinum and its potential medical benefits. After trials on monkeys in the 1970s, it was first used in humans in 1980 for the treatment of strabismus. *The FDA (Food and Drug Administration) is the U.S. government body responsible for regulating food, drugs, and cosmetics. For more detailed information, please visit https://en.wikipedia.org/wiki/Food_and_Drug_Administration.

This text has been specially prepared for Dr. Ebru DURMUŞ. Unauthorized use without reference is strictly prohibited. Dr. Ebru DURMUŞ is a well-known aesthetic specialist in Izmir, performing wrinkle treatment, lip fillers, and cellulite treatments.